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“There is a clear need for alternative treatments prior to surgery that […] slow or reverse the progression of intervertebral disc degeneration,” said Jiangang Shi, professor in the Department of Orthopedic Surgery in Changzheng Hospital from Navy Medical University and co-lead author of the study published in Advanced Biology

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The choice changes how much control there is over each compound's dose and schedule, and how much injection-site management is needed